2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Acetolactate Synthase (ALS)

Acetolactate Synthase (ALS)

Acetohydroxyacid synthase

Acetohydroxyacid synthase (ALS), a thiamine diphosphate-dependent enzyme, can condense either two pyruvate molecules to form acetolactate for synthesizing Lvaline and L-leucine or pyruvate with 2-ketobutyrate to form acetohydroxybutyrate for synthesizing L-isoleucine. Because the key reaction catalyzed by acetohydroxyacid synthase in the biosynthetic pathways of branched-chain amino acids (valine, leucine, and isoleucine) exists in plants, fungi, archaea, and bacteria, but not in animals, acetohydroxyacid synthase becomes a potential target for developing novel herbicides and antimicrobial compounds.

Acetolactate Synthase (ALS) Related Products (23):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100427
    Imazamox
    		99.69%
    Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.
    Imazamox
  • HY-B1876
    Nicosulfuron
    		Inhibitor
    Nicosulfuron is efficient, harmless, antifungal and selective herbicide belonging to the sulfonylurea family. Nicosulfuron is also a photosynthetic system inhibitor and inhibits acetolactate synthase (ALS) enzyme activity. Nicosulfuron degradation by Plectosphaerella cucumerina AR1 is glucose concentration dependent in planktonic lifestyle. Nicosulfuron enhances the glycolysis pathway and tricarboxylic acid cycle to improve the adaptability of sweet maize. Nicosulfuron reduces the synthesis of branched-chain amino acids (BCAAs), which is proming for maize cultivation.
    Nicosulfuron
  • HY-B1847
    Terbuthylazine
    		≥98.0%
    Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide.
    Terbuthylazine
  • HY-119737
    Chlorsulfuron
    		98.47%
    Chlorsulfuron blocks the biosynthesis of the amino acids valine and isoleucine in plants. Chlorsulfuron completely alleviates herbicide-induced growth inhibition. The site of action of Chlorsulfuron is the enzyme acetolactate synthase.
    Chlorsulfuron
  • HY-B0865
    Pyrazosulfuron-ethyl
    		98.42%
    Pyrazosulfuron-ethyl, one of the acetolactate synthase inhibiting herbicides in the sulphonylurea family, has been widely used to control weed growth in commercial cereal, soybean, and vegetable fields.
    Pyrazosulfuron-ethyl
  • HY-B1847R
    Terbuthylazine (Standard)
    Terbuthylazine (Standard) is the analytical standard of Terbuthylazine. This product is intended for research and analytical applications.
    Terbuthylazine (Standard)
  • HY-B0865R
    Pyrazosulfuron-ethyl (Standard)
    Pyrazosulfuron-ethyl (Standard) is the analytical standard of Pyrazosulfuron-ethyl. This product is intended for research and analytical applications. Pyrazosulfuron-ethyl, one of the acetolactate synthase inhibiting herbicides in the sulphonylurea family, has been widely used to control weed growth in commercial cereal, soybean, and vegetable fields.
    Pyrazosulfuron-ethyl (Standard)
  • HY-121727
    Triafamone
    		Inhibitor
    Triafamone (AE 1887196) is a paddy field pre-emergence and post-emergence sulfonamide herbicide. Triafamone weeds by inhibiting the acetolactate synthase (ALS) enzyme, thereby blocking the biosynthesis of branched-chain amino acids.
    Triafamone
  • HY-B0869A
    Bispyribac sodium
    		99.56%
    Bispyribac sodium is a selective, systemic and post emergent herbicide used to eradicate grasses and broad leaf weeds. Bispyribac sodium is also an acetolactate synthase (ALS or known as AHAS) inhibitor.
    Bispyribac sodium
  • HY-100427S
    Imazamox-13C,d3
    		99.63%
    Imazamox-13C,d3 is the 13C- and deuterium labeled Imazamox. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death[1][2].
    Imazamox-<sup>13</sup>C,d<sub>3</sub>
  • HY-100427R
    Imazamox (Standard)
    Imazamox (Standard) is the analytical standard of Imazamox. This product is intended for research and analytical applications. Imazamox (CL29926) is a systemic herbicide that inhibits the production of acetolactate synthase (ALS) in plants with high selectivity, high activity, safety and broadspectrum activity, which would then inhibit plant growth and ultimately lead to plant death.
    Imazamox (Standard)
  • HY-B1876R
    Nicosulfuron (Standard)
    Nicosulfuron (Standard) is the analytical standard of Nicosulfuron. This product is intended for research and analytical applications. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity.
    Nicosulfuron (Standard)
  • HY-B1847S1
    Terbuthylazine-d5
    		99.13%
    Terbuthylazine-d5 is the deuterium labeled Terbuthylazine[1]. Terbuthylazine is an inhibitor of acetolactate syntase (ALS), is a selective herbicide[2].
    Terbuthylazine-d<sub>5</sub>
  • HY-W422402
    Foramsulfuron
    		Inhibitor
    Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids.
    Foramsulfuron
  • HY-B1876S
    Nicosulfuron-d6
    Nicosulfuron-d6 is the deuterium labeled Nicosulfuron[1]. Nicosulfuron is a selective herbicide belonging to the sulfonylurea family. Nicosulfuron is commonly used as a post-emergence herbicide to protect maize crops from weeds. Nicosulfuron inhibits acetolactate synthase (ALS) enzyme activity[2].
    Nicosulfuron-d<sub>6</sub>
  • HY-158245
    Herbicide safener-2
    Herbicide safener-2 (Compound III-7) is a herbicide safener with the same pharmacokinetic profile as the safener mefenpyr-diethyl (HY-136376). Herbicide safener-2 competitively binds to the acetolactate synthase (ALS) active site with mesosulfuron-methyl (HY-126987). Herbicide safener-2 protects crops against herbicide injury.
    Herbicide safener-2
  • HY-W422402R
    Foramsulfuron (Standard)
    		Inhibitor
    Foramsulfuron (Standard) is the analytical standard of Foramsulfuron. This product is intended for research and analytical applications. Foramsulfuron is a postemergence herbicide used for selective control of grass and some broadleaved weeds in maize (Zea mays L.). Foramsulfuron is a sulfonylurea herbicide that exerts its herbicidal activity by inhibiting acetolactate synthase (ALS), a key enzyme in the biosynthesis of branched chain amino acids.
    Foramsulfuron (Standard)
  • HY-119737R
    Chlorsulfuron (Standard)
    Chlorsulfuron (Standard) is the analytical standard of Chlorsulfuron. This product is intended for research and analytical applications. Chlorsulfuron blocks the biosynthesis of the amino acids valine and isoleucine in plants. Chlorsulfuron completely alleviates herbicide-induced growth inhibition. The site of action of Chlorsulfuron is the enzyme acetolactate synthase.
    Chlorsulfuron (Standard)
  • HY-126987
    Mesosulfuron-methyl
    		Inhibitor
    Mesosulfuron-methyl is a sulfonylurea herbicide that inhibits acetolactate synthase (ALS) and is used in research for post-emergence control of ryegrass and Avena spp. (wild oat) in wheat fields.
    Mesosulfuron-methyl
  • HY-126176
    Cloransulam-methyl
    		Inhibitor
    Cloransulam-methyl is a triazolopyrimidine sulfonanilide herbicide. Cloransulam-methyl can be used to control broadleaf weeds in soybean by acetolactate synthase (ALS) inhibition.
    Cloransulam-methyl